Name | Riboflavin |
Synonyms | E 101 vitasanb2 VITAMIN G Riboflavin Vitamin B2 xypentyl)- Vitamin B_2 Riboflavine Lactoflavine Riboflavin (VB2) RIBOFLAVIN DC GRADE Riboflavin (1.07609) Riboflavin Vitamin B2 Vitamin B2 Feed Grade Vitamin B2 (Riboflavine) RIBOFLAVIN USP (VITAMIN B-2) 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol 5-deoxy-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol |
CAS | 83-88-5 |
EINECS | 201-507-1 |
InChI | InChI=1/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1 |
InChIKey | AUNGANRZJHBGPY-SCRDCRAPSA-N |
Molecular Formula | C17H20N4O6 |
Molar Mass | 376.36 |
Density | 1.2112 (rough estimate) |
Melting Point | 290°C (dec.)(lit.) |
Boling Point | 504.93°C (rough estimate) |
Specific Rotation(α) | -135 º (c=5, 0.05 M NaOH) |
Flash Point | 9℃ |
Water Solubility | 0.07 g/L (20 ºC) |
Solubility | Very slightly soluble in water, practically insoluble in ethanol (96 per cent). Solutions deteriorate on exposure to light, especially in the presence of alkali. It shows polymorphism (5.9). |
Appearance | Powder |
Color | Yellow to orange |
Odor | Slight odour |
Merck | 14,8200 |
BRN | 97825 |
pKa | 1.7(at 25℃) |
PH | 5.5-7.2 (0.07g/l, H2O, 20°C) |
Storage Condition | 2-8°C |
Stability | Stable, but light-sensitive. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. May be moisture sensitive. |
Sensitive | Light Sensitive |
Refractive Index | -135 ° (C=0.5, JP Me |
MDL | MFCD00005022 |
Physical and Chemical Properties | Melting Point 290°C specific optical rotation -135 ° (c = 5, 0.05 M NaOH) water-soluble 0.07g/L (20°C) |
Use | For the treatment of riboflavin deficiency, conjunctivitis, nutritional ulcers, General Nutrition disorders and other diseases |
Risk Codes | R11 - Highly Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R39/23/24/25 - |
Safety Description | S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. |
UN IDs | UN1230 - class 3 - PG 2 - Methanol, solution |
WGK Germany | 1 |
RTECS | VJ1400000 |
FLUKA BRAND F CODES | 8-10-21 |
TSCA | Yes |
HS Code | 29362300 |
Toxicity | LD50 in rats (g/kg): >10 orally, 5.0 s.c., 0.56 i.p. (Unna, Greslin) |
Raw Materials | Starch potato |
yellow to orange-yellow crystalline powder, slightly odorous, slightly bitter in taste. Soluble in alkaline solution and sodium chloride solution, slightly soluble in water, slightly soluble in ethanol, insoluble in ether and chloroform. The aqueous solution is yellow green, and the saturated aqueous solution is neutral. Heat resistance, acid resistance is good, in alkaline solution or by ultraviolet radiation is vulnerable to damage, the reducing agent is not stable.
with glucose, corn steep liquor and inorganic salt as culture medium, it was prepared by submerged fermentation with special active bacteria. Vitamin B2 can also be obtained from the condensation of 3,4-= methylaniline with D-ribose by catalytic hydrogenation, coupling, reduction and cyclization.
vitamin B2 is a vitamin that promotes the growth and development of the body. It can participate in many redox reactions in the body and promote the growth by promoting the oxidative decomposition of carbohydrates, lipids and proteins. Lack of vitamin B2, will lead to the decline of tissue respiration, the body's metabolic process disorders. Susceptible to conjunctivitis, mouth fire, glossitis and other symptoms. China's provisions can be used for salt, the use of 100 ~ 150mg/kg; The maximum use of 10 ~ 13mg/kg in solid beverages; The use of 4 ~ 8mg/kg in baby food; the amount used is 3.0~5.0 mg/kg in cereal and its products, and 1~2 mg/kg in drink and milk drink. Also available as a yellow colorant.